Last Updated: Jul 16, 2020, 07:17 AM IST

MUMBAI: Ahmedabad-based Zydus Cadila on Wednesday said it has begun the adaptive phase-I and II human trials of its plasmid DNA vaccine for Covid-19.

The company said in the preclinical stage the vaccine was found to be safe, immunogenic and well-tolerated. It was also able to produce neutralising antibodies in animal studies, a key requirement for a vaccine. In the phase-I and II trials, the company will assess the safety, tolerability and immunogenicity of the vaccine.

The puzzle on our new vaccine will be solved after the Phase-III trials … we are hopeful that if all goes well, the vaccine will be out in the first half of 2021,” chairman Pankaj Patel told ET. The DNA vaccine platform of the company provides ease of manufacturing the vaccine with minimal biosafety requirements. The platform is also known to show much improved vaccine stability and lower cold-chain requirements, making it easy for transportation to remote regions of the country.